null
SMILES: CCCCCCCCSc1ccc(cc1)C(=O)Nc1cc(C)ccc1C(O)=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human)) | BDBM50582014 (CHEMBL5076395) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.81E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to full length PLK1 (367 to 603 residues) (unknown origin) using MAGPMQS[pT]PLNGAKK tracer peptide as substrate by fluorescence pola... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00133 BindingDB Entry DOI: 10.7270/Q2TH8RK0 | |||||||||||
More data for this Ligand-Target Pair |