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SMILES: Oc1ccc(cc1)-c1oc2ccc(O)c(CN3CCC4(COC4)C3)c2c1C(=O)N1CC(F)C1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582182   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50582182 (CHEMBL5091803) Show SMILES Oc1ccc(cc1)-c1oc2ccc(O)c(CN3CCC4(COC4)C3)c2c1C(=O)N1CC(F)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of hERG ion channel by Q patch-clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01586 BindingDB Entry DOI: 10.7270/Q24T6P88
					More data for this Ligand-Target Pair
Polyketide synthase Pks13 (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50582182 (CHEMBL5091803) Show SMILES Oc1ccc(cc1)-c1oc2ccc(O)c(CN3CCC4(COC4)C3)c2c1C(=O)N1CC(F)C1 Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Mycobacterium tuberculosis Pks13-TE domain using 4-methylumbelliferyl heptanoate as a fluorogenic substrate measured for 110 mins at 10...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01586 BindingDB Entry DOI: 10.7270/Q24T6P88
					More data for this Ligand-Target Pair