null
SMILES: [H][C@@]12CN([C@@]([H])(CN1C(=O)C=C)C2)S(=O)(=O)c1ccc(cc1)N1CC(CN2CCC(CC2)[C@@](CN2CCC2)(c2cccc(F)c2)[C@@]2([H])CCC[C@@H]2NC(=O)OC)(C1)OC
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Menin (Homo sapiens (Human)) | BDBM50582752 (CHEMBL5085064) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00789 BindingDB Entry DOI: 10.7270/Q2GX4GFD | |||||||||||
More data for this Ligand-Target Pair |