null
SMILES: Cc1nn(C)cc1N1CCC(NC(=O)Nc2ccc(Br)cc2)C1=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-formyl peptide receptor 2 (Homo sapiens (Human)) | BDBM50582815![]() (CHEMBL5078594) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 142 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at FPRL1 (unknown origin) expressed in CHO-K1 cells assessed as increase in calcium mobilization incubated for 2.5 hrs by cellular b... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113805 BindingDB Entry DOI: 10.7270/Q2QF8XRP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-formyl peptide receptor 2 (Homo sapiens (Human)) | BDBM50582815![]() (CHEMBL5078594) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 4.88E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human FPR2 expressed in HEK293-A cells assessed as ERK phosphorylation level incubated for 5 mins by ELISA assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113805 BindingDB Entry DOI: 10.7270/Q2QF8XRP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-formyl peptide receptor 2 (Homo sapiens (Human)) | BDBM50582815![]() (CHEMBL5078594) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 740 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at FPRL1 (unknown origin) expressed in CHO-K1 cells assessed as stimulation of beta-arrestin recruitment incubated for 150 mins by b... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113805 BindingDB Entry DOI: 10.7270/Q2QF8XRP | |||||||||||
More data for this Ligand-Target Pair |