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SMILES: Cc1n(nc2c1c(C)nn(CCCC(=O)NCCc1ccc(NC(=O)CCCCCCNC(=O)CC34CC5CC(CC(C5)C3)C4)cc1)c2=O)-c1ccc(C)cc1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50583522   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta


(Homo sapiens (Human))		BDBM50583522
PNG
(CHEMBL5082602)
Show SMILES Cc1n(nc2c1c(C)nn(CCCC(=O)NCCc1ccc(NC(=O)CCCCCCNC(=O)CC34CC5CC(CC(C5)C3)C4)cc1)c2=O)-c1ccc(C)cc1 |TLB:38:39:36.37.42:43,THB:38:37:43:44.39.40,40:39:36:42.41.43,40:41:36:44.38.39|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 147n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity to PDE delta (unknown origin) assessed as dissociation constant measured after 2 hrs by fluorescence polarization assay

Citation and Details

Article DOI: 10.1021/acsmedchemlett.1c00670
BindingDB Entry DOI: 10.7270/Q2PC368T
More data for this
Ligand-Target Pair