null
SMILES: [H][C@]12CN([C@@H](Cc3cc4OCOc4c(OC)c3)CN1C(=O)\C(=C\c1ccc(O)c(OC)c1)[C@]2([H])c1cc2OCOc2c(OC)c1)C(C)=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50584539 (CHEMBL5082663) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of P-glycoprotein overexpressed in human SW620/AD300 cells assessed as reversal of doxorubicin resistance by measuring doxorubicin IC50 at... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01989 BindingDB Entry DOI: 10.7270/Q2QZ2FV4 | |||||||||||
More data for this Ligand-Target Pair |