null
SMILES: CN(C)C(=O)[C@H]1CSCc2c(Br)cccc2C(=O)OC[C@@H](NC(=O)[C@@H]2CCCN2C(C)=O)C(=O)N1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human)) | BDBM50584788 (CHEMBL5094633) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Keap1-Nrf2 (unknown origin) interaction assessed as dissociation constant by surface plasmon resonance based inhibition-in-solution ass... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01975 BindingDB Entry DOI: 10.7270/Q2FJ2MQS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human)) | BDBM50584788 (CHEMBL5094633) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Keap1-Nrf2 (unknown origin) interaction assessed as dissociation constant by isothermal titration calorimetry | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01975 BindingDB Entry DOI: 10.7270/Q2FJ2MQS | |||||||||||
More data for this Ligand-Target Pair |