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SMILES: COc1ccc2CSC[C@@H](NC(=O)[C@@H](COC(=O)c2c1)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N(C)C

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50584799   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear factor erythroid 2-related factor 2


(Homo sapiens (Human))		BDBM50584799
PNG
(CHEMBL5087113)
Show SMILES COc1ccc2CSC[C@@H](NC(=O)[C@@H](COC(=O)c2c1)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N(C)C |r|
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 2.04E+5n/an/an/an/an/a


TBA

Assay Description
Inhibition of Keap1-Nrf2 (unknown origin) interaction assessed as dissociation constant by surface plasmon resonance based inhibition-in-solution ass...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01975
BindingDB Entry DOI: 10.7270/Q2FJ2MQS
More data for this
Ligand-Target Pair