null
SMILES: CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(C)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human)) | BDBM50585049 (CHEMBL5075321) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of DYRK1B (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human)) | BDBM50585049 (CHEMBL5075321) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB | |||||||||||
More data for this Ligand-Target Pair |