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SMILES: Cc1cc(Nc2cc(nc(Nc3ccc(CC(=O)NC4CC4)cc3)n2)N2CCN(CCO)CC2)[nH]n1

InChI Key:

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50585639   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase receptor Ret


(Homo sapiens (Human))		BDBM50585639
PNG
(CHEMBL5075257)
Show SMILES Cc1cc(Nc2cc(nc(Nc3ccc(CC(=O)NC4CC4)cc3)n2)N2CCN(CCO)CC2)[nH]n1
PDB
MMDB

KEGG

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PC cid
PC sid
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Article
PubMed
n/an/a 22n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of GST-3C fused human RET (705 to 1013 residues) expressed in sf9 baculovirus expression system using 5-FAM- peptide as substrate preincub...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01280
BindingDB Entry DOI: 10.7270/Q24X5CPK
More data for this
Ligand-Target Pair