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SMILES: CC(C)(O)c1ccc(NC(=O)c2cccc(c2F)-c2ccccc2OCC(F)(F)F)cc1

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50585899   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ceramide glucosyltransferase


(Homo sapiens (Human))		BDBM50585899
PNG
(CHEMBL5086168)
Show SMILES CC(C)(O)c1ccc(NC(=O)c2cccc(c2F)-c2ccccc2OCC(F)(F)F)cc1
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KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 45n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hr by RapidFire mass spectrometry

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c02078
BindingDB Entry DOI: 10.7270/Q2KW5KZB
More data for this
Ligand-Target Pair