null
SMILES: CS(=O)(=O)C1(CNCc2ccc(Cl)c3cccnc23)CC1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM50585907 (CHEMBL5082447) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.25E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]-5-CT from human 5-HT5A receptor incubated for 2 hr by radioligand binding assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02031 BindingDB Entry DOI: 10.7270/Q2G73JM6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM50585907 (CHEMBL5082447) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 3.63E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human 5-HT5A receptor transfected in HTLA cells assessed as increase in beta-arrestin 2 recruitment at 10 uM incubated for 18 to ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02031 BindingDB Entry DOI: 10.7270/Q2G73JM6 | |||||||||||
More data for this Ligand-Target Pair |