null

SMILES: CC(C)C[C@](C)(N)COc1ncc(cc1C)-c1ccnc(c1)C(F)F

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50586144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50586144 (CHEMBL5074638) Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C)-c1ccnc(c1)C(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50586144 (CHEMBL5074638) Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C)-c1ccnc(c1)C(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02131 BindingDB Entry DOI: 10.7270/Q2X63RT2
					More data for this Ligand-Target Pair