Search and Browse
Download
Enter Data
null
SMILES: CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cc(Cl)ccc3C)n(Cc3ccco3)c(=O)c21
InChI Key:
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50586215 (CHEMBL5080392) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of BRD4-BD1 (unknown origin) incubated for 6 hrs by HTRF method | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50586215 (CHEMBL5080392) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of BRD4-BD2 (unknown origin) incubated for 6 hrs by HTRF method | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 3 (Homo sapiens (Human)) | BDBM50586215 (CHEMBL5080392) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF method | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 3 (Homo sapiens (Human)) | BDBM50586215 (CHEMBL5080392) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of BRD3-BD1 domain (unknown origin) incubated for 6 hrs by HTRF method | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 2 (Homo sapiens (Human)) | BDBM50586215 (CHEMBL5080392) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human partial length BRD2-BD2 (E348 to D455) expressed in bacterial system assessed as dissociation constant by BROMOscan method | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 3 (Homo sapiens (Human)) | BDBM50586215 (CHEMBL5080392) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 325 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human partial length BRD3-BD2 (G306 to P416) expressed in bacterial system assessed as dissociation constant by BROMOscan method | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50586215 (CHEMBL5080392) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 775 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human partial length BRD4-BD2 (K333 to E460 residues) expressed in bacterial system assessed as dissociation constant by BROMOsca... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bromodomain-containing protein 2 (Homo sapiens (Human)) | BDBM50586215 (CHEMBL5080392) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of BRD2-BD2 (unknown origin) incubated for 6 hrs by HTRF method | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02168 BindingDB Entry DOI: 10.7270/Q20Z7752 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
