null
SMILES: CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCNC(=O)CCc2nc3cc(O)ccc3[nH]2)cc1)c1ccccc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50586409![]() (CHEMBL5088360) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02230 BindingDB Entry DOI: 10.7270/Q26H4N92 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50586409![]() (CHEMBL5088360) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02230 BindingDB Entry DOI: 10.7270/Q26H4N92 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50586409![]() (CHEMBL5088360) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation by dual luciferase ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02230 BindingDB Entry DOI: 10.7270/Q26H4N92 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50586409![]() (CHEMBL5088360) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at ERalpha (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation by dual luciferase... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02230 BindingDB Entry DOI: 10.7270/Q26H4N92 | |||||||||||
More data for this Ligand-Target Pair |