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SMILES: CN(C(c1ccccc1)c1ccccc1)C(=O)Cn1ccnc1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50587165   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Heme oxygenase 1


(Rattus norvegicus (rat))
BDBM50587165
PNG
(CHEMBL5081981)
Show SMILES CN(C(c1ccccc1)c1ccccc1)C(=O)Cn1ccnc1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 900n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometry


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00633
BindingDB Entry DOI: 10.7270/Q23F4TJN
More data for this
Ligand-Target Pair
Heme oxygenase 2


(Rattus norvegicus (rat))
BDBM50587165
PNG
(CHEMBL5081981)
Show SMILES CN(C(c1ccccc1)c1ccccc1)C(=O)Cn1ccnc1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 900n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometry


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00633
BindingDB Entry DOI: 10.7270/Q23F4TJN
More data for this
Ligand-Target Pair