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SMILES: Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2nc3cc(ccc3nc12)C#N

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50598837   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Homo sapiens (Human))	BDBM50598837 (CHEMBL5187022) Show SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2nc3cc(ccc3nc12)C#N |(3.87,-3.29,;4.16,-2.09,;5.64,-1.66,;6,-.16,;4.89,.9,;5.18,2.1,;3.41,.47,;2.52,1.32,;3.05,-1.03,;1.54,-1.35,;.92,-2.76,;1.53,-3.83,;-.61,-2.6,;-1.64,-3.74,;-2.85,-3.49,;-1.26,-4.91,;-.93,-1.09,;-2.27,-.32,;-2.27,1.22,;-3.6,1.99,;-3.6,3.53,;-2.27,4.3,;-.93,3.53,;-.93,1.99,;.4,1.22,;.4,-.32,;-4.94,4.3,;-6,4.91,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00552 BindingDB Entry DOI: 10.7270/Q2028WKQ
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Homo sapiens (Human))	BDBM50598837 (CHEMBL5187022) Show SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2nc3cc(ccc3nc12)C#N |(3.87,-3.29,;4.16,-2.09,;5.64,-1.66,;6,-.16,;4.89,.9,;5.18,2.1,;3.41,.47,;2.52,1.32,;3.05,-1.03,;1.54,-1.35,;.92,-2.76,;1.53,-3.83,;-.61,-2.6,;-1.64,-3.74,;-2.85,-3.49,;-1.26,-4.91,;-.93,-1.09,;-2.27,-.32,;-2.27,1.22,;-3.6,1.99,;-3.6,3.53,;-2.27,4.3,;-.93,3.53,;-.93,1.99,;.4,1.22,;.4,-.32,;-4.94,4.3,;-6,4.91,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00552 BindingDB Entry DOI: 10.7270/Q2028WKQ
					More data for this Ligand-Target Pair