null
SMILES: Cn1cc(cn1)-c1nc(N[C@@H]2CCCC[C@@H]2N)c(Cl)c2CNC(=O)c12
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Interleukin 1 receptor associated kinase 4 (Dog) | BDBM510496 (US11077111, Compound IVa | US20230295171, Example ...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A radiometric protein kinase assay was used for measuring the kinase activity of the Dog (Canis lupus familiaris) IRAK4, JAK1, JAK2, SYK kinases. All... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35XS9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase (Dog) | BDBM510496 (US11077111, Compound IVa | US20230295171, Example ...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 466 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A radiometric protein kinase assay was used for measuring the kinase activity of the Dog (Canis lupus familiaris) IRAK4, JAK1, JAK2, SYK kinases. All... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35XS9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM510496 (US11077111, Compound IVa | US20230295171, Example ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 3.16 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase (Dog) | BDBM510496 (US11077111, Compound IVa | US20230295171, Example ...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 323 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A radiometric protein kinase assay was used for measuring the kinase activity of the Dog (Canis lupus familiaris) IRAK4, JAK1, JAK2, SYK kinases. All... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35XS9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase (Dog) | BDBM510496 (US11077111, Compound IVa | US20230295171, Example ...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 624 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A radiometric protein kinase assay was used for measuring the kinase activity of the Dog (Canis lupus familiaris) IRAK4, JAK1, JAK2, SYK kinases. All... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35XS9 | |||||||||||
More data for this Ligand-Target Pair |