Found 5 hits for monomerid = 513695 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2
(Homo sapiens (Human)) | BDBM513695
(US11091495, Example 56 | US11220509, Example 56 | ...)Show SMILES Cc1nc(ccc1-c1cnc(NCc2c3CCOc3ccc2F)n2cc(nc12)C#N)N1CCOCC1 | PDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2V69NQ4 |
More data for this
Ligand-Target Pair | |
Histone-binding protein RBBP4/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2
(Homo sapiens (Human)) | BDBM513695
(US11091495, Example 56 | US11220509, Example 56 | ...)Show SMILES Cc1nc(ccc1-c1cnc(NCc2c3CCOc3ccc2F)n2cc(nc12)C#N)N1CCOCC1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2HQ43R4 |
More data for this
Ligand-Target Pair | |
Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2
(Homo sapiens (Human)) | BDBM513695
(US11091495, Example 56 | US11220509, Example 56 | ...)Show SMILES Cc1nc(ccc1-c1cnc(NCc2c3CCOc3ccc2F)n2cc(nc12)C#N)N1CCOCC1 | PDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2J969K9 |
More data for this
Ligand-Target Pair | |
Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2
(Homo sapiens (Human)) | BDBM513695
(US11091495, Example 56 | US11220509, Example 56 | ...)Show SMILES Cc1nc(ccc1-c1cnc(NCc2c3CCOc3ccc2F)n2cc(nc12)C#N)N1CCOCC1 | PDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2J969K9 |
More data for this
Ligand-Target Pair | |
Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2
(Homo sapiens (Human)) | BDBM513695
(US11091495, Example 56 | US11220509, Example 56 | ...)Show SMILES Cc1nc(ccc1-c1cnc(NCc2c3CCOc3ccc2F)n2cc(nc12)C#N)N1CCOCC1 | PDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2J969K9 |
More data for this
Ligand-Target Pair | |
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