null
SMILES: C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(OC(F)(F)F)c(NC(=O)C=C)c2)C(=O)N1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MAP kinase-activated protein kinase 2 (Homo sapiens (Human)) | BDBM515436![]() (US11098061, Compound III-45) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Briefly, a 1.25× stock of MK-2 enzyme from Invitrogen (PV3317), a 5× stock of ATP (AS001A), and ST3-Sox peptide substrate (KNZ1031C) were prepared in... | Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4NZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-activated protein kinase 2 (Homo sapiens (Human)) | BDBM515436![]() (US11098061, Compound III-45) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <100 | n/a | n/a | n/a | n/a |
TBA | Assay Description Briefly, a 1.25× stock of MK-2 enzyme from Invitrogen (PV3317), a 5× stock of ATP (AS001A), and ST3-Sox peptide substrate (KNZ1031C) were prepared in... | Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4NZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-activated protein kinase 2 (Homo sapiens (Human)) | BDBM515436![]() (US11098061, Compound III-45) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Briefly, a 1.25× stock of MK-2 enzyme from Invitrogen (PV3317), a 5× stock of ATP (AS001A), and ST3-Sox peptide substrate (KNZ1031C) were prepared in... | Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4NZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
MAP kinase-activated protein kinase 2 (Homo sapiens (Human)) | BDBM515436![]() (US11098061, Compound III-45) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <100 | n/a | n/a | n/a | n/a |
TBA | Assay Description Briefly, a 1.25× stock of MK-2 enzyme from Invitrogen (PV3317), a 5× stock of ATP (AS001A), and ST3-Sox peptide substrate (KNZ1031C) were prepared in... | Citation and Details BindingDB Entry DOI: 10.7270/Q2XW4NZW | |||||||||||
More data for this Ligand-Target Pair |