null

SMILES: FC(F)(F)c1cc(COC(=O)N2C[C@H]3C(CNC(=O)c4ccc5n[nH]nc5c4)[C@H]3C2)cc(c1)C(F)(F)F

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516893   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM516893 (US11104665, ACS Med. Chem. Lett. 2017, 8, 1252-125...) Show SMILES FC(F)(F)c1cc(COC(=O)N2C[C@H]3C(CNC(=O)c4ccc5n[nH]nc5c4)[C@H]3C2)cc(c1)C(F)(F)F Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2, 1 mM MgCl2 0.14 mM NaCl, and ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VX0KN7
					More data for this Ligand-Target Pair