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null

SMILES: CNc1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 521025
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521025 (US11149020, Compound 16 (MW-200)) Show SMILES CNc1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
TBA					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM521025 (US11149020, Compound 16 (MW-200)) Show SMILES CNc1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
TBA					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM521025 (US11149020, Compound 16 (MW-200)) Show SMILES CNc1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2251NBP
TBA					More data for this Ligand-Target Pair