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SMILES: CCOc1ccc(C2=C(c3ccc(O[C@H]4CCN(CCCF)C4)nc3)c3ccc(O)cc3SC2)c(F)n1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 521255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor [298-554] (Homo sapiens (Human))	BDBM521255 (3-(6-ethoxy-2- fluoro-3- pyridyl)-4-[6- [(3S)-1-(3...) Show SMILES CCOc1ccc(C2=C(c3ccc(O[C@H]4CCN(CCCF)C4)nc3)c3ccc(O)cc3SC2)c(F)n1 |r,c:7| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521255 (3-(6-ethoxy-2- fluoro-3- pyridyl)-4-[6- [(3S)-1-(3...) Show SMILES CCOc1ccc(C2=C(c3ccc(O[C@H]4CCN(CCCF)C4)nc3)c3ccc(O)cc3SC2)c(F)n1 |r,c:7| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,D538G] (Homo sapiens (Human))	BDBM521255 (3-(6-ethoxy-2- fluoro-3- pyridyl)-4-[6- [(3S)-1-(3...) Show SMILES CCOc1ccc(C2=C(c3ccc(O[C@H]4CCN(CCCF)C4)nc3)c3ccc(O)cc3SC2)c(F)n1 |r,c:7| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair