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SMILES: Oc1ccc2c(CCCC(c3ccc(Cl)cc3Cl)=C2c2ccc(N[C@H]3CCN(CCCF)C3)cc2)c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 521261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor [298-554] (Homo sapiens (Human))	BDBM521261 (6-(2,4- dichlorophenyl)- 5-[4-[[(3S)-1- (3- fluoro...) Show SMILES Oc1ccc2c(CCCC(c3ccc(Cl)cc3Cl)=C2c2ccc(N[C@H]3CCN(CCCF)C3)cc2)c1 |r,c:18| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521261 (6-(2,4- dichlorophenyl)- 5-[4-[[(3S)-1- (3- fluoro...) Show SMILES Oc1ccc2c(CCCC(c3ccc(Cl)cc3Cl)=C2c2ccc(N[C@H]3CCN(CCCF)C3)cc2)c1 |r,c:18| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair
Estrogen receptor [298-554,D538G] (Homo sapiens (Human))	BDBM521261 (6-(2,4- dichlorophenyl)- 5-[4-[[(3S)-1- (3- fluoro...) Show SMILES Oc1ccc2c(CCCC(c3ccc(Cl)cc3Cl)=C2c2ccc(N[C@H]3CCN(CCCF)C3)cc2)c1 |r,c:18| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair