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SMILES: Nc1ncnn2c(ccc12)[C@@]1(O[C@](CF)(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#N

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 521556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Human rhinovirus 16)	BDBM521556 (((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...) Show SMILES Nc1ncnn2c(ccc12)[C@@]1(O[C@](CF)(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#N |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63PG
					More data for this Ligand-Target Pair
Rous sarcoma virus integrase (Rous sarcoma virus (strain Prague C) (RSV-PrC))	BDBM521556 (((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...) Show SMILES Nc1ncnn2c(ccc12)[C@@]1(O[C@](CF)(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#N |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Standard RSV polymerase assays were conducted in the presence of 3 μL extract of RSV-infected cells in a reaction buffer containing 50 mM tris-a...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63PG
					More data for this Ligand-Target Pair
Genome polyprotein (DENV-1)	BDBM521556 (((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...) Show SMILES Nc1ncnn2c(ccc12)[C@@]1(O[C@](CF)(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzyme activity of dengue virus NS5 polymerase domain (DENVpol, serotype 2, New Guinea C strain) was measured as an incorporation of tritiated NM...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63PG
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM521556 (((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...) Show SMILES Nc1ncnn2c(ccc12)[C@@]1(O[C@](CF)(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#N |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63PG
					More data for this Ligand-Target Pair