null
SMILES: CCOC(=O)c1cc(C)nn1-c1ccc(CN2C(=O)Cc3cnc(nc23)-c2ccccc2C2CC2)cc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human)) | BDBM522541 (US11161848, Compound I-99 | ethyl 1-(4-((2-(2-) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning... | Citation and Details BindingDB Entry DOI: 10.7270/Q2TH8QWM | |||||||||||
More data for this Ligand-Target Pair |