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SMILES: C[C@H]1CN(CCN1C1CCOC1)c1cc(ncn1)-n1ncc2ccc(cc12)[C@]1(CC11CC1)C#N

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 523058   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 [1-1200,1251-2527,G2019S] (Homo sapiens (Human))	BDBM523058 (US11161854, Example 3.8-1 | US11161854, Example 3....) Show SMILES C[C@H]1CN(CCN1C1CCOC1)c1cc(ncn1)-n1ncc2ccc(cc12)[C@]1(CC11CC1)C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, C...				Citation and Details BindingDB Entry DOI: 10.7270/Q29K4FC3
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [1-1200,1251-2527,G2019S] (Homo sapiens (Human))	BDBM523058 (US11161854, Example 3.8-1 | US11161854, Example 3....) Show SMILES C[C@H]1CN(CCN1C1CCOC1)c1cc(ncn1)-n1ncc2ccc(cc12)[C@]1(CC11CC1)C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, C...				Citation and Details BindingDB Entry DOI: 10.7270/Q29K4FC3
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [1-1200,1251-2527,G2019S] (Homo sapiens (Human))	BDBM523058 (US11161854, Example 3.8-1 | US11161854, Example 3....) Show SMILES C[C@H]1CN(CCN1C1CCOC1)c1cc(ncn1)-n1ncc2ccc(cc12)[C@]1(CC11CC1)C#N |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, C...				Citation and Details BindingDB Entry DOI: 10.7270/Q29K4FC3
					More data for this Ligand-Target Pair