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SMILES: C[C@H]1CN(CCN1S(C)(=O)=O)c1cc(ccn1)-n1ncc2ccc(cc12)[C@@]1(CC11CC1)C#N

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 523124   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2 [1-1200,1251-2527,G2019S]


(Homo sapiens (Human))		BDBM523124
PNG
(US11161854, Example 6.5)
Show SMILES C[C@H]1CN(CCN1S(C)(=O)=O)c1cc(ccn1)-n1ncc2ccc(cc12)[C@@]1(CC11CC1)C#N |r|
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 1.5n/an/an/an/an/an/a


TBA

Assay Description
The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, C...

Citation and Details

BindingDB Entry DOI: 10.7270/Q29K4FC3
More data for this
Ligand-Target Pair