null

SMILES: COc1ccc(c(OC)c1)S(=O)(=O)NC(=O)c1ccc(nc1N1C[C@@H](C)CC1(C)C)-n1ccc(OCC2(CC2)C(F)(F)F)n1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 526474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator [1-507,509-1480] (Homo sapiens (Human))	BDBM526474 (US11186566, Compound 13) Show SMILES COc1ccc(c(OC)c1)S(=O)(=O)NC(=O)c1ccc(nc1N1C[C@@H](C)CC1(C)C)-n1ccc(OCC2(CC2)C(F)(F)F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
TBA					Assay Description The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...				Citation and Details BindingDB Entry DOI: 10.7270/Q22R3VVH
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator [1-507,509-1480] (Homo sapiens (Human))	BDBM526474 (US11186566, Compound 13) Show SMILES COc1ccc(c(OC)c1)S(=O)(=O)NC(=O)c1ccc(nc1N1C[C@@H](C)CC1(C)C)-n1ccc(OCC2(CC2)C(F)(F)F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
TBA					Assay Description The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...				Citation and Details BindingDB Entry DOI: 10.7270/Q22R3VVH
					More data for this Ligand-Target Pair