null

SMILES: COc1ccccc1C(Cn1c2sc(c(C)c2c(=O)n(-c2c(C)ccn3ccnc23)c1=O)-c1ncco1)OC1CCOCC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 527005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 1 (Homo sapiens (Human))	BDBM527005 (US11186587, Example 5) Show SMILES COc1ccccc1C(Cn1c2sc(c(C)c2c(=O)n(-c2c(C)ccn3ccnc23)c1=O)-c1ncco1)OC1CCOCC1 |(-2.19,-3.85,;-.86,-3.08,;.47,-3.85,;.47,-5.39,;1.81,-6.16,;3.14,-5.39,;3.14,-3.85,;1.81,-3.08,;1.81,-1.54,;.47,-.77,;.47,.77,;-.86,1.54,;-2.33,1.06,;-3.23,2.31,;-2.33,3.56,;-2.8,5.02,;-.86,3.08,;.47,3.85,;.47,5.39,;1.81,3.08,;3.14,3.85,;3.14,5.39,;1.81,6.16,;4.47,6.16,;5.81,5.39,;5.81,3.85,;6.95,2.82,;6.33,1.41,;4.79,1.57,;4.47,3.08,;1.81,1.54,;3.14,.77,;-4.77,2.31,;-5.68,3.56,;-7.14,3.08,;-7.14,1.54,;-5.68,1.06,;3.14,-.77,;4.47,-1.54,;4.47,-3.08,;5.81,-3.85,;7.14,-3.08,;7.14,-1.54,;5.81,-.77,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...				Citation and Details BindingDB Entry DOI: 10.7270/Q25H7KFV
					More data for this Ligand-Target Pair