BindingDB PrimarySearch

null

SMILES: COCc1nn(Cc2cnc(nc2)N2CCCC2)cc1C(=O)NCc1c(F)c(OC)ccc1-n1cnnn1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 528127
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Plasma kallikrein (Homo sapiens (Human))	BDBM528127 (US11180484, Example 79 \| US11180484, Reference Exa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SP5
TBA				More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM528127 (US11180484, Example 79 \| US11180484, Reference Exa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SP5
TBA				More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM528127 (US11180484, Example 79 \| US11180484, Reference Exa...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SP5
TBA				More data for this Ligand-Target Pair
Coagulation factor XII (Homo sapiens (Human))	BDBM528127 (US11180484, Example 79 \| US11180484, Reference Exa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SP5
TBA				More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM528127 (US11180484, Example 79 \| US11180484, Reference Exa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SP5
TBA				More data for this Ligand-Target Pair
Kallikrein-1 (Homo sapiens (Human))	BDBM528127 (US11180484, Example 79 \| US11180484, Reference Exa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SP5
TBA				More data for this Ligand-Target Pair
Serine protease 1 (Homo sapiens (Human))	BDBM528127 (US11180484, Example 79 \| US11180484, Reference Exa...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SP5
TBA				More data for this Ligand-Target Pair
Coagulation factor XII (Homo sapiens (Human))	BDBM528127 (US11180484, Example 79 \| US11180484, Reference Exa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SP5
TBA				More data for this Ligand-Target Pair
Plasma serine protease inhibitor (Human)	BDBM528127 (US11180484, Example 79 \| US11180484, Reference Exa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SP5
TBA				More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM528127 (US11180484, Example 79 \| US11180484, Reference Exa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	7.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SP5
TBA				More data for this Ligand-Target Pair
Kallikrein-1 (Homo sapiens (Human))	BDBM528127 (US11180484, Example 79 \| US11180484, Reference Exa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SP5
TBA				More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM528127 (US11180484, Example 79 \| US11180484, Reference Exa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SP5
TBA				More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM528127 (US11180484, Example 79 \| US11180484, Reference Exa...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SP5
TBA				More data for this Ligand-Target Pair