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SMILES: CNc1cc(cn(C)c1=O)-c1cc(NS(=O)(=O)C=C)ccc1Oc1ccc(C)cc1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 528583   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [353-454]


(Homo sapiens (Human))		BDBM528583
PNG
(US11192900, Compound 4 | US11192900, Example S-11)
Show SMILES CNc1cc(cn(C)c1=O)-c1cc(NS(=O)(=O)C=C)ccc1Oc1ccc(C)cc1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 22n/an/an/an/an/an/a


TBA

Assay Description
The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2XS5ZJK
More data for this
Ligand-Target Pair