null
SMILES: CCNC(=O)c1cc2c(s1)c(cn(C)c2=O)-c1cc(NC(=O)\C=C\C)ccc1Oc1c(C)cccc1C
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 4 [353-454] (Homo sapiens (Human)) | BDBM528643![]() (US11192900, Compound 611 | US11192900, Example S-6...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con... | Citation and Details BindingDB Entry DOI: 10.7270/Q2XS5ZJK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [58-164] (Homo sapiens (Human)) | BDBM528643![]() (US11192900, Compound 611 | US11192900, Example S-6...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con... | Citation and Details BindingDB Entry DOI: 10.7270/Q2XS5ZJK | |||||||||||
More data for this Ligand-Target Pair |