BDBM52877 MLS000518376::SMR000440494::cid_11949179

SMILES: [H][C@]12CN(Cc3ccc(cc3)C(F)(F)F)[C@H](c3ccccc3)C11CC(C1)(C2c1ccccc1)c1ccc(cc1)C(=O)OC

InChI Key: InChIKey=FGNVWFVQBRWEIN-DHQHLYBYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 52877   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
POsterior Segregation family member (pos-1) (Caenorhabditis elegans)	BDBM52877 (MLS000518376 | SMR000440494 | cid_11949179) Show SMILES [H][C@]12CN(Cc3ccc(cc3)C(F)(F)F)[C@H](c3ccccc3)C11CC(C1)(C2c1ccccc1)c1ccc(cc1)C(=O)OC |wU:1.0,15.16,(11.35,-.65,;12.41,-1.42,;11.17,-2.33,;11.64,-3.78,;10.74,-5.03,;9.21,-4.87,;8.58,-3.46,;7.05,-3.3,;6.14,-4.55,;6.77,-5.95,;8.3,-6.11,;4.61,-4.38,;3.08,-4.22,;4.45,-5.92,;4.77,-2.85,;13.17,-3.78,;14.08,-5.03,;13.45,-6.44,;14.35,-7.68,;15.88,-7.53,;16.51,-6.12,;15.61,-4.87,;13.65,-2.33,;14.9,-1.42,;14.42,.04,;13.61,-1,;12.88,.04,;11.98,1.29,;12.6,2.69,;11.7,3.94,;10.17,3.78,;9.54,2.37,;10.44,1.13,;14.9,1.51,;16.4,1.83,;16.88,3.29,;15.85,4.43,;14.34,4.11,;13.87,2.65,;16.32,5.9,;15.29,7.04,;17.83,6.22,;18.31,7.68,)| Show InChI InChI=1S/C36H32F3NO2/c1-42-33(41)27-14-18-28(19-15-27)34-22-35(23-34)30(31(34)25-8-4-2-5-9-25)21-40(32(35)26-10-6-3-7-11-26)20-24-12-16-29(17-13-24)36(37,38)39/h2-19,30-32H,20-23H2,1H3/t30-,31?,32-,34?,35?/m1/s1	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q28G8J4C
					More data for this Ligand-Target Pair
RecName: Full=Zinc finger protein mex-5 (Caenorhabditis elegans)	BDBM52877 (MLS000518376 | SMR000440494 | cid_11949179) Show SMILES [H][C@]12CN(Cc3ccc(cc3)C(F)(F)F)[C@H](c3ccccc3)C11CC(C1)(C2c1ccccc1)c1ccc(cc1)C(=O)OC |wU:1.0,15.16,(11.35,-.65,;12.41,-1.42,;11.17,-2.33,;11.64,-3.78,;10.74,-5.03,;9.21,-4.87,;8.58,-3.46,;7.05,-3.3,;6.14,-4.55,;6.77,-5.95,;8.3,-6.11,;4.61,-4.38,;3.08,-4.22,;4.45,-5.92,;4.77,-2.85,;13.17,-3.78,;14.08,-5.03,;13.45,-6.44,;14.35,-7.68,;15.88,-7.53,;16.51,-6.12,;15.61,-4.87,;13.65,-2.33,;14.9,-1.42,;14.42,.04,;13.61,-1,;12.88,.04,;11.98,1.29,;12.6,2.69,;11.7,3.94,;10.17,3.78,;9.54,2.37,;10.44,1.13,;14.9,1.51,;16.4,1.83,;16.88,3.29,;15.85,4.43,;14.34,4.11,;13.87,2.65,;16.32,5.9,;15.29,7.04,;17.83,6.22,;18.31,7.68,)| Show InChI InChI=1S/C36H32F3NO2/c1-42-33(41)27-14-18-28(19-15-27)34-22-35(23-34)30(31(34)25-8-4-2-5-9-25)21-40(32(35)26-10-6-3-7-11-26)20-24-12-16-29(17-13-24)36(37,38)39/h2-19,30-32H,20-23H2,1H3/t30-,31?,32-,34?,35?/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2D798VP
					More data for this Ligand-Target Pair