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SMILES: Fc1ccccc1C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)CC2

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 532239   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM532239 (US11208422, Example 80 | US11208422, Example 81) Show SMILES Fc1ccccc1C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)CC2 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5XHD
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM532239 (US11208422, Example 80 | US11208422, Example 81) Show SMILES Fc1ccccc1C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5XHD
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM532239 (US11208422, Example 80 | US11208422, Example 81) Show SMILES Fc1ccccc1C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)CC2 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5XHD
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM532239 (US11208422, Example 80 | US11208422, Example 81) Show SMILES Fc1ccccc1C(=O)N1C2CCC1CN(Cc1c(nc3ncccn13)-c1ccc(Cl)cc1)CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5XHD
					More data for this Ligand-Target Pair