null

SMILES: CC(C)C(C(=O)N1C[C@H](O)C[C@H]1C1=NC(=O)[C@@](C)(N1)c1ccc(Br)cc1)c1cc(C)no1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 536184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Elongin-B/Elongin-C [17-112]/von Hippel-Lindau disease tumor suppressor [55-213] (Homo sapiens (Human))	BDBM536184 (5-(4-Bromophenyl)-2-((4R)-4-hydroxy-1-(3-methyl-2-...) Show SMILES CC(C)C(C(=O)N1C[C@H](O)C[C@H]1C1=NC(=O)[C@@](C)(N1)c1ccc(Br)cc1)c1cc(C)no1 |r,t:13| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KW5K7X
					More data for this Ligand-Target Pair
Elongin-B/Elongin-C [17-112]/von Hippel-Lindau disease tumor suppressor [55-213] (Homo sapiens (Human))	BDBM536184 (5-(4-Bromophenyl)-2-((4R)-4-hydroxy-1-(3-methyl-2-...) Show SMILES CC(C)C(C(=O)N1C[C@H](O)C[C@H]1C1=NC(=O)[C@@](C)(N1)c1ccc(Br)cc1)c1cc(C)no1 |r,t:13| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KW5K7X
					More data for this Ligand-Target Pair