null

SMILES: CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C1=NOC(C)(C)N1)c1cc(C)no1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 536203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Elongin-B/Elongin-C [17-112]/von Hippel-Lindau disease tumor suppressor [55-213] (Homo sapiens (Human))	BDBM536203 ((R)-1-((2S,4R)-2-(5,5-dimethyl-4,5-dihydro-1,2,4-o...) Show SMILES CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C1=NOC(C)(C)N1)c1cc(C)no1 |r,t:13| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KW5K7X
					More data for this Ligand-Target Pair
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human))	BDBM536203 ((R)-1-((2S,4R)-2-(5,5-dimethyl-4,5-dihydro-1,2,4-o...) Show SMILES CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C1=NOC(C)(C)N1)c1cc(C)no1 |r,t:13| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The VHL NanoBRET™ Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL Nano...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KW5K7X
					More data for this Ligand-Target Pair
Elongin-B/Elongin-C [17-112]/von Hippel-Lindau disease tumor suppressor [55-213] (Homo sapiens (Human))	BDBM536203 ((R)-1-((2S,4R)-2-(5,5-dimethyl-4,5-dihydro-1,2,4-o...) Show SMILES CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C1=NOC(C)(C)N1)c1cc(C)no1 |r,t:13| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KW5K7X
					More data for this Ligand-Target Pair