null
SMILES: CC(C)[C@H](C(=O)N1C[C@H](O)C[C@@H]1C1=NC(=O)C(C)(N1)c1ccc(cc1)-c1scnc1C)c1cc(OCCCCCNC(=O)c2cc3N(Cc4c[nH]c5c4c(cn(C)c5=O)-c3cc2CS(C)(=O)=O)c2ncc(F)cc2F)no1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Elongin-B/Elongin-C [17-112]/von Hippel-Lindau disease tumor suppressor [55-213] (Homo sapiens (Human)) | BDBM536277 (US11242344, Example 1001.2 | US11242344, Example 1...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KW5K7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Elongin-B/Elongin-C [17-112]/von Hippel-Lindau disease tumor suppressor [55-213] (Homo sapiens (Human)) | BDBM536277 (US11242344, Example 1001.2 | US11242344, Example 1...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 795 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin... | Citation and Details BindingDB Entry DOI: 10.7270/Q2KW5K7X | |||||||||||
More data for this Ligand-Target Pair |