null

SMILES: COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOCC#CC#CCOc1cc(on1)[C@@H](C(C)C)C(=O)N1C[C@H](O)C[C@H]1C1=NC(=O)[C@@](C)(N1)c1ccc(cc1)-c1scnc1C

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 536291   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human))	BDBM536291 ((5S)-2-((4R)-1-(2-(3-((6-(2-((4-((3-Ethynylphenyl)...) Show SMILES COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOCC#CC#CCOc1cc(on1)[C@@H](C(C)C)C(=O)N1C[C@H](O)C[C@H]1C1=NC(=O)[C@@](C)(N1)c1ccc(cc1)-c1scnc1C |r,t:57| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The VHL NanoBRET™ Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL Nano...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KW5K7X
					More data for this Ligand-Target Pair
Elongin-B/Elongin-C [17-112]/von Hippel-Lindau disease tumor suppressor [55-213] (Homo sapiens (Human))	BDBM536291 ((5S)-2-((4R)-1-(2-(3-((6-(2-((4-((3-Ethynylphenyl)...) Show SMILES COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOCC#CC#CCOc1cc(on1)[C@@H](C(C)C)C(=O)N1C[C@H](O)C[C@H]1C1=NC(=O)[C@@](C)(N1)c1ccc(cc1)-c1scnc1C |r,t:57| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KW5K7X
					More data for this Ligand-Target Pair