BDBM53907 2-(5-amino-1,3,4-thiadiazol-2-yl)-N'-{3-bromo-2-hydroxy-5-nitrobenzylidene}acetohydrazide::2-(5-amino-1,3,4-thiadiazol-2-yl)-N'-[(E)-(5-bromo-3-nitro-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]acetohydrazide::2-(5-amino-1,3,4-thiadiazol-2-yl)-N'-[(E)-(5-bromo-3-nitro-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]acetohydrazide::2-(5-amino-1,3,4-thiadiazol-2-yl)-N'-[(E)-(5-bromo-6-keto-3-nitro-cyclohexa-2,4-dien-1-ylidene)methyl]acetohydrazide::2-(5-azanyl-1,3,4-thiadiazol-2-yl)-N'-[(E)-(5-bromanyl-3-nitro-6-oxidanylidene-cyclohexa-2,4-dien-1-ylidene)methyl]ethanehydrazide::MLS000705091::SMR000230750::cid_16189248

SMILES: Nc1nnc(CC(=O)N\[NH+]=C\[c-]2cc(cc(Br)c2=O)[N+]([O-])=O)s1

InChI Key: InChIKey=JOGNNXYVYUFRSA-LNKIKWGQSA-O

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 53907   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Zinc aminopeptidase (Plasmodium falciparum (isolate FcB1 / Columbia))	BDBM53907 (2-(5-amino-1,3,4-thiadiazol-2-yl)-N'-{3-bromo-...) Show SMILES Nc1nnc(CC(=O)N\[NH+]=C\[c-]2cc(cc(Br)c2=O)[N+]([O-])=O)s1 Show InChI InChI=1S/C11H8BrN6O4S/c12-7-2-6(18(21)22)1-5(10(7)20)4-14-15-8(19)3-9-16-17-11(13)23-9/h1-2,4H,3H2,(H2,13,17)(H,15,19)/q-1/p+1/b14-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q27H1H0J
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM53907 (2-(5-amino-1,3,4-thiadiazol-2-yl)-N'-{3-bromo-...) Show SMILES Nc1nnc(CC(=O)N\[NH+]=C\[c-]2cc(cc(Br)c2=O)[N+]([O-])=O)s1 Show InChI InChI=1S/C11H8BrN6O4S/c12-7-2-6(18(21)22)1-5(10(7)20)4-14-15-8(19)3-9-16-17-11(13)23-9/h1-2,4H,3H2,(H2,13,17)(H,15,19)/q-1/p+1/b14-4+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2J67FCM
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM53907 (2-(5-amino-1,3,4-thiadiazol-2-yl)-N'-{3-bromo-...) Show SMILES Nc1nnc(CC(=O)N\[NH+]=C\[c-]2cc(cc(Br)c2=O)[N+]([O-])=O)s1 Show InChI InChI=1S/C11H8BrN6O4S/c12-7-2-6(18(21)22)1-5(10(7)20)4-14-15-8(19)3-9-16-17-11(13)23-9/h1-2,4H,3H2,(H2,13,17)(H,15,19)/q-1/p+1/b14-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.09E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DF6PNW
					More data for this Ligand-Target Pair
Alpi (Rattus norvegicus (Rat))	BDBM53907 (2-(5-amino-1,3,4-thiadiazol-2-yl)-N'-{3-bromo-...) Show SMILES Nc1nnc(CC(=O)N\[NH+]=C\[c-]2cc(cc(Br)c2=O)[N+]([O-])=O)s1 Show InChI InChI=1S/C11H8BrN6O4S/c12-7-2-6(18(21)22)1-5(10(7)20)4-14-15-8(19)3-9-16-17-11(13)23-9/h1-2,4H,3H2,(H2,13,17)(H,15,19)/q-1/p+1/b14-4+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2DB809V
					More data for this Ligand-Target Pair
Alkaline phosphatase placental-like (Homo sapiens (Human))	BDBM53907 (2-(5-amino-1,3,4-thiadiazol-2-yl)-N'-{3-bromo-...) Show SMILES Nc1nnc(CC(=O)N\[NH+]=C\[c-]2cc(cc(Br)c2=O)[N+]([O-])=O)s1 Show InChI InChI=1S/C11H8BrN6O4S/c12-7-2-6(18(21)22)1-5(10(7)20)4-14-15-8(19)3-9-16-17-11(13)23-9/h1-2,4H,3H2,(H2,13,17)(H,15,19)/q-1/p+1/b14-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2NS0SCW
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM53907 (2-(5-amino-1,3,4-thiadiazol-2-yl)-N'-{3-bromo-...) Show SMILES Nc1nnc(CC(=O)N\[NH+]=C\[c-]2cc(cc(Br)c2=O)[N+]([O-])=O)s1 Show InChI InChI=1S/C11H8BrN6O4S/c12-7-2-6(18(21)22)1-5(10(7)20)4-14-15-8(19)3-9-16-17-11(13)23-9/h1-2,4H,3H2,(H2,13,17)(H,15,19)/q-1/p+1/b14-4+	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2H130G1
					More data for this Ligand-Target Pair
Intestinal alkaline phosphatase (Homo sapiens (Human))	BDBM53907 (2-(5-amino-1,3,4-thiadiazol-2-yl)-N'-{3-bromo-...) Show SMILES Nc1nnc(CC(=O)N\[NH+]=C\[c-]2cc(cc(Br)c2=O)[N+]([O-])=O)s1 Show InChI InChI=1S/C11H8BrN6O4S/c12-7-2-6(18(21)22)1-5(10(7)20)4-14-15-8(19)3-9-16-17-11(13)23-9/h1-2,4H,3H2,(H2,13,17)(H,15,19)/q-1/p+1/b14-4+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2X63KDM
					More data for this Ligand-Target Pair