BDBM54378 MLS001045934::N-[1-(2-Chloro-benzyl)-1H-benzoimidazol-2-yl]-propionamide::N-[1-(2-chlorobenzyl)benzimidazol-2-yl]propionamide::N-[1-[(2-chlorophenyl)methyl]-2-benzimidazolyl]propanamide::N-[1-[(2-chlorophenyl)methyl]benzimidazol-2-yl]propanamide::SMR000425174::cid_914315

SMILES: CCC(=O)Nc1nc2ccccc2n1Cc1ccccc1Cl

InChI Key: InChIKey=GKHGYBSFLVZHND-UHFFFAOYSA-N

Data: 11 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 54378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
nucleotide-binding oligomerization domain containing 2 (Homo sapiens (Human))	BDBM54378 (MLS001045934 | N-[1-(2-Chloro-benzyl)-1H-benzoimid...) Show SMILES CCC(=O)Nc1nc2ccccc2n1Cc1ccccc1Cl Show InChI InChI=1S/C17H16ClN3O/c1-2-16(22)20-17-19-14-9-5-6-10-15(14)21(17)11-12-7-3-4-8-13(12)18/h3-10H,2,11H2,1H3,(H,19,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R8T
					More data for this Ligand-Target Pair
streptokinase A precursor (Streptococcus pyogenes M1 GAS)	BDBM54378 (MLS001045934 | N-[1-(2-Chloro-benzyl)-1H-benzoimid...) Show SMILES CCC(=O)Nc1nc2ccccc2n1Cc1ccccc1Cl Show InChI InChI=1S/C17H16ClN3O/c1-2-16(22)20-17-19-14-9-5-6-10-15(14)21(17)11-12-7-3-4-8-13(12)18/h3-10H,2,11H2,1H3,(H,19,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV
					More data for this Ligand-Target Pair
nucleotide-binding oligomerization domain containing 1 (Homo sapiens (Human))	BDBM54378 (MLS001045934 | N-[1-(2-Chloro-benzyl)-1H-benzoimid...) Show SMILES CCC(=O)Nc1nc2ccccc2n1Cc1ccccc1Cl Show InChI InChI=1S/C17H16ClN3O/c1-2-16(22)20-17-19-14-9-5-6-10-15(14)21(17)11-12-7-3-4-8-13(12)18/h3-10H,2,11H2,1H3,(H,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CN72C0
					More data for this Ligand-Target Pair
nucleotide-binding oligomerization domain containing 1 (Homo sapiens (Human))	BDBM54378 (MLS001045934 | N-[1-(2-Chloro-benzyl)-1H-benzoimid...) Show SMILES CCC(=O)Nc1nc2ccccc2n1Cc1ccccc1Cl Show InChI InChI=1S/C17H16ClN3O/c1-2-16(22)20-17-19-14-9-5-6-10-15(14)21(17)11-12-7-3-4-8-13(12)18/h3-10H,2,11H2,1H3,(H,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2Z899VD
					More data for this Ligand-Target Pair
nucleotide-binding oligomerization domain containing 1 (Homo sapiens (Human))	BDBM54378 (MLS001045934 | N-[1-(2-Chloro-benzyl)-1H-benzoimid...) Show SMILES CCC(=O)Nc1nc2ccccc2n1Cc1ccccc1Cl Show InChI InChI=1S/C17H16ClN3O/c1-2-16(22)20-17-19-14-9-5-6-10-15(14)21(17)11-12-7-3-4-8-13(12)18/h3-10H,2,11H2,1H3,(H,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2Z899VD
					More data for this Ligand-Target Pair
nucleotide-binding oligomerization domain containing 2 (Homo sapiens (Human))	BDBM54378 (MLS001045934 | N-[1-(2-Chloro-benzyl)-1H-benzoimid...) Show SMILES CCC(=O)Nc1nc2ccccc2n1Cc1ccccc1Cl Show InChI InChI=1S/C17H16ClN3O/c1-2-16(22)20-17-19-14-9-5-6-10-15(14)21(17)11-12-7-3-4-8-13(12)18/h3-10H,2,11H2,1H3,(H,19,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2TH8K43
					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM54378 (MLS001045934 | N-[1-(2-Chloro-benzyl)-1H-benzoimid...) Show SMILES CCC(=O)Nc1nc2ccccc2n1Cc1ccccc1Cl Show InChI InChI=1S/C17H16ClN3O/c1-2-16(22)20-17-19-14-9-5-6-10-15(14)21(17)11-12-7-3-4-8-13(12)18/h3-10H,2,11H2,1H3,(H,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q25M6443
					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM54378 (MLS001045934 | N-[1-(2-Chloro-benzyl)-1H-benzoimid...) Show SMILES CCC(=O)Nc1nc2ccccc2n1Cc1ccccc1Cl Show InChI InChI=1S/C17H16ClN3O/c1-2-16(22)20-17-19-14-9-5-6-10-15(14)21(17)11-12-7-3-4-8-13(12)18/h3-10H,2,11H2,1H3,(H,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2PR7TDC
					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM54378 (MLS001045934 | N-[1-(2-Chloro-benzyl)-1H-benzoimid...) Show SMILES CCC(=O)Nc1nc2ccccc2n1Cc1ccccc1Cl Show InChI InChI=1S/C17H16ClN3O/c1-2-16(22)20-17-19-14-9-5-6-10-15(14)21(17)11-12-7-3-4-8-13(12)18/h3-10H,2,11H2,1H3,(H,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2PR7TDC
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM54378 (MLS001045934 | N-[1-(2-Chloro-benzyl)-1H-benzoimid...) Show SMILES CCC(=O)Nc1nc2ccccc2n1Cc1ccccc1Cl Show InChI InChI=1S/C17H16ClN3O/c1-2-16(22)20-17-19-14-9-5-6-10-15(14)21(17)11-12-7-3-4-8-13(12)18/h3-10H,2,11H2,1H3,(H,19,20,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2TD9VS8
					More data for this Ligand-Target Pair
nucleotide-binding oligomerization domain containing 2 (Homo sapiens (Human))	BDBM54378 (MLS001045934 | N-[1-(2-Chloro-benzyl)-1H-benzoimid...) Show SMILES CCC(=O)Nc1nc2ccccc2n1Cc1ccccc1Cl Show InChI InChI=1S/C17H16ClN3O/c1-2-16(22)20-17-19-14-9-5-6-10-15(14)21(17)11-12-7-3-4-8-13(12)18/h3-10H,2,11H2,1H3,(H,19,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2JW8CBM
					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM54378 (MLS001045934 | N-[1-(2-Chloro-benzyl)-1H-benzoimid...) Show SMILES CCC(=O)Nc1nc2ccccc2n1Cc1ccccc1Cl Show InChI InChI=1S/C17H16ClN3O/c1-2-16(22)20-17-19-14-9-5-6-10-15(14)21(17)11-12-7-3-4-8-13(12)18/h3-10H,2,11H2,1H3,(H,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q29C6VV1
					More data for this Ligand-Target Pair
nucleotide-binding oligomerization domain containing 2 (Homo sapiens (Human))	BDBM54378 (MLS001045934 | N-[1-(2-Chloro-benzyl)-1H-benzoimid...) Show SMILES CCC(=O)Nc1nc2ccccc2n1Cc1ccccc1Cl Show InChI InChI=1S/C17H16ClN3O/c1-2-16(22)20-17-19-14-9-5-6-10-15(14)21(17)11-12-7-3-4-8-13(12)18/h3-10H,2,11H2,1H3,(H,19,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2TH8K43
					More data for this Ligand-Target Pair