null
SMILES: CC(C)c1cc(-c2nc(c3CC[C@@H]4[C@@H](C)C(=O)C(=C[C@@]4(C)c3n2)C#N)-c2ccccc2F)c2ccccc2n1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nuclear receptor ROR-gamma (Homo sapiens (Human)) | BDBM546640![]() (US11292781, Compound T123) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The RORγ assay system was purchased from Indigo Biosciences. This nuclear receptor assay utilizes a human cell line that has been engineered to ... | Citation and Details BindingDB Entry DOI: 10.7270/Q24F1TXR | |||||||||||
More data for this Ligand-Target Pair |