BindingDB PrimarySearch

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SMILES: CCCc1nc(cc2n(C)c(C(=O)N3CCN(C)CC3)c(C)c12)-n1ncc2c(C)nc(cc12)-c1cnccc1OC

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 547888
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Epidermal growth factor receptor [1-18,20-1210,T790M,C797S] (Homo sapiens (Human))	BDBM547888 (WO2022090481, Example I-107) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor/Interleukin-3 (Homo sapiens (Human))	BDBM547888 (WO2022090481, Example I-107) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	633	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM547888 (WO2022090481, Example I-107) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	249	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Epidermal growth factor receptor [1-18,20-1210] (Homo sapiens (Human))	BDBM547888 (WO2022090481, Example I-107) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	5.45	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor [1-18,20-1210,T790M] (Homo sapiens (Human))	BDBM547888 (WO2022090481, Example I-107) Show SMILES Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	6.06	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Epidermal growth factor receptor [L858R,T790M,C797S] (Homo sapiens (Human))	BDBM547888 (WO2022090481, Example I-107) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Epidermal growth factor receptor [1-18,20-1210,T790M,C797S] (Homo sapiens (Human))	BDBM547888 (WO2022090481, Example I-107) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	5.42	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Epidermal growth factor receptor [L858R] (Homo sapiens (Human))	BDBM547888 (WO2022090481, Example I-107) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Epidermal growth factor receptor [T790M,L858R] (Homo sapiens (Human))	BDBM547888 (WO2022090481, Example I-107) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Epidermal growth factor receptor [L858R,C797S] (Homo sapiens (Human))	BDBM547888 (WO2022090481, Example I-107) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Epidermal growth factor receptor [1-18,20-1210,C797S] (Homo sapiens (Human))	BDBM547888 (WO2022090481, Example I-107) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	7.07	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair