BindingDB PrimarySearch

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SMILES: COc1ccncc1-c1cc2n(ncc2c(C)n1)-c1cc2n(C)c(nc2c(n1)N1C[C@H]2C[C@@H]1CO2)N1CCN(CC2CC2)CC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 547965
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Epidermal growth factor receptor [1-18,20-1210,T790M,C797S] (Homo sapiens (Human))	BDBM547965 (WO2022090481, Example I-186) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor/Interleukin-3 (Homo sapiens (Human))	BDBM547965 (WO2022090481, Example I-186) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM547965 (WO2022090481, Example I-186) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Epidermal growth factor receptor [1-18,20-1210] (Homo sapiens (Human))	BDBM547965 (WO2022090481, Example I-186) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Epidermal growth factor receptor [1-18,20-1210,T790M] (Homo sapiens (Human))	BDBM547965 (WO2022090481, Example I-186) Show SMILES Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Epidermal growth factor receptor [L858R,T790M,C797S] (Homo sapiens (Human))	BDBM547965 (WO2022090481, Example I-186) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Epidermal growth factor receptor [1-18,20-1210,T790M,C797S] (Homo sapiens (Human))	BDBM547965 (WO2022090481, Example I-186) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Epidermal growth factor receptor [L858R] (Homo sapiens (Human))	BDBM547965 (WO2022090481, Example I-186) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Epidermal growth factor receptor [T790M,L858R] (Homo sapiens (Human))	BDBM547965 (WO2022090481, Example I-186) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Epidermal growth factor receptor [L858R,C797S] (Homo sapiens (Human))	BDBM547965 (WO2022090481, Example I-186) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Epidermal growth factor receptor [1-18,20-1210,C797S] (Homo sapiens (Human))	BDBM547965 (WO2022090481, Example I-186) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair