BDBM548880 WO2022098806, Compound 2-141

SMILES: CC1CNc2c(C)c(cnc2O1)-c1cc2nc(Nc3ccc4CCN(C)Cc4c3)ncc2c(N)c1F

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 548880   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human))	BDBM548880 (WO2022098806, Compound 2-141) Show SMILES CC1CNc2c(C)c(cnc2O1)-c1cc2nc(Nc3ccc4CCN(C)Cc4c3)ncc2c(N)c1F Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
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