BDBM54951 (6Z)-3-(2-furanyl)-6-(2-pyrrolylidene)-5H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole::(6Z)-3-(2-furyl)-6-pyrrol-2-ylidene-5H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole::(6Z)-3-(furan-2-yl)-6-pyrrol-2-ylidene-5H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole::VU0364701-1::cid_44236874

SMILES: c1c[nH]c(c1)-c1nn2c(nnc2s1)-c1ccco1

InChI Key: InChIKey=LTMAUFULSATPJT-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 54951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
mitogen-activated protein kinase kinase kinase 3 isoform 1 (Homo sapiens (Human))	BDBM54951 ((6Z)-3-(2-furanyl)-6-(2-pyrrolylidene)-5H-[1,2,4]t...) Show SMILES c1c[nH]c(c1)-c1nn2c(nnc2s1)-c1ccco1 Show InChI InChI=1S/C11H7N5OS/c1-3-7(12-5-1)10-15-16-9(8-4-2-6-17-8)13-14-11(16)18-10/h1-6,12H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q81BH4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 2 (Homo sapiens (Human))	BDBM54951 ((6Z)-3-(2-furanyl)-6-(2-pyrrolylidene)-5H-[1,2,4]t...) Show SMILES c1c[nH]c(c1)-c1nn2c(nnc2s1)-c1ccco1 Show InChI InChI=1S/C11H7N5OS/c1-3-7(12-5-1)10-15-16-9(8-4-2-6-17-8)13-14-11(16)18-10/h1-6,12H	MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2FQ9V13
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 2 (Homo sapiens (Human))	BDBM54951 ((6Z)-3-(2-furanyl)-6-(2-pyrrolylidene)-5H-[1,2,4]t...) Show SMILES c1c[nH]c(c1)-c1nn2c(nnc2s1)-c1ccco1 Show InChI InChI=1S/C11H7N5OS/c1-3-7(12-5-1)10-15-16-9(8-4-2-6-17-8)13-14-11(16)18-10/h1-6,12H	MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2KH0KRZ
					More data for this Ligand-Target Pair