null
SMILES: Cc1cc(Nc2ncnc3sc(cc23)C(=O)N2CC(C2)NC(=O)OC(C)(C)C)c(=O)n2c1C(=O)NC21CCCC1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human)) | BDBM550568 (US11311520, Example 62 | tert-Butyl [1-({4-[(8R...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description MKNK1-inhibitory activity at high ATP of compounds of the present invention after their preincubation with MKNK1 was quantified employing the TR-FRET... | Citation and Details BindingDB Entry DOI: 10.7270/Q2VT1W9T | |||||||||||
More data for this Ligand-Target Pair |