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SMILES: Cc1cc(Nc2ncnc3sc(cc23)C(=O)N2CC(N)C2)c(=O)n2c1C(=O)NC21CCCC1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550580   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-interacting serine/threonine-protein kinase 1


(Homo sapiens (Human))		BDBM550580
PNG
(6′-({6-[(3-Aminoazetidin-1-yl)carbonyl]thien...)
Show SMILES Cc1cc(Nc2ncnc3sc(cc23)C(=O)N2CC(N)C2)c(=O)n2c1C(=O)NC21CCCC1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 1.5n/an/an/an/an/an/a


TBA

Assay Description
MKNK1-inhibitory activity at high ATP of compounds of the present invention after their preincubation with MKNK1 was quantified employing the TR-FRET...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2VT1W9T
More data for this
Ligand-Target Pair