null

SMILES: CC1CC(CN(C1)c1cn(nc1C)C(C)(C)CO)c1nc2c3cc(F)cc(F)c3nc(N)n2n1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 551631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM551631 (2-(4-((3R,5S or 3S,5R)-3-(5-amino-7,9-difluoro- [1...) Show SMILES CC1CC(CN(C1)c1cn(nc1C)C(C)(C)CO)c1nc2c3cc(F)cc(F)c3nc(N)n2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...				Citation and Details BindingDB Entry DOI: 10.7270/Q2639SZ0
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM551631 (2-(4-((3R,5S or 3S,5R)-3-(5-amino-7,9-difluoro- [1...) Show SMILES CC1CC(CN(C1)c1cn(nc1C)C(C)(C)CO)c1nc2c3cc(F)cc(F)c3nc(N)n2n1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...				Citation and Details BindingDB Entry DOI: 10.7270/Q2639SZ0
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM551631 (2-(4-((3R,5S or 3S,5R)-3-(5-amino-7,9-difluoro- [1...) Show SMILES CC1CC(CN(C1)c1cn(nc1C)C(C)(C)CO)c1nc2c3cc(F)cc(F)c3nc(N)n2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...				Citation and Details BindingDB Entry DOI: 10.7270/Q2639SZ0
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM551631 (2-(4-((3R,5S or 3S,5R)-3-(5-amino-7,9-difluoro- [1...) Show SMILES CC1CC(CN(C1)c1cn(nc1C)C(C)(C)CO)c1nc2c3cc(F)cc(F)c3nc(N)n2n1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...				Citation and Details BindingDB Entry DOI: 10.7270/Q2639SZ0
					More data for this Ligand-Target Pair