null
SMILES: COc1cc2nc(N)n3nc(nc3c2cc1F)C1CC(C)CN(C1)c1cnn(CC(C)(C)O)c1C
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM551728 (1-((4-((3R,5S or 3S,5R)-5-(5-amino-9-fluoro-8-meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2639SZ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2b (Homo sapiens (Human)) | BDBM551728 (1-((4-((3R,5S or 3S,5R)-5-(5-amino-9-fluoro-8-meth...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2639SZ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM551728 (1-((4-((3R,5S or 3S,5R)-5-(5-amino-9-fluoro-8-meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15.6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2639SZ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2b (Homo sapiens (Human)) | BDBM551728 (1-((4-((3R,5S or 3S,5R)-5-(5-amino-9-fluoro-8-meth...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 70.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM... | Citation and Details BindingDB Entry DOI: 10.7270/Q2639SZ0 | |||||||||||
More data for this Ligand-Target Pair |